文摘

镇痛、抗炎症和体外细胞毒性的影响穿心莲香墙。交货需要雇

作者(年代):R。罗陀,。Farheen Jerad苏雷什,B。乌玛,M.Lavanya

摘要目的:评估镇痛,anti-infllammatory和体外的细胞毒性的影响ethanolic提取穿心莲香墙前需要雇。材料与方法:树叶的ethanolic提取物的镇痛活性制剂香(EAP)墙。交货需要雇were reported to have analgesic activity but the activity has still not reported in stem. The analgesic activity ofAndrographis paniculata was studied in mice by hot plate method, tail clip method and acetic acid induced writhing method. The anti-inflammatory activity of the EAP was studied in rats by carrageenan induced paw edema method. Two different doses of EAP extract (200mg/kg of 400mg/kg bodyweight) of animals were tested.结果:EAP(400毫克/公斤)显示显著的镇痛活动使用的所有三种方法提取而200毫克/公斤AP显示重要的活动只使用醋酸诱导扭动方法。EAP提取还显示显著的抗炎活性。EAP被发现细胞毒性的体外模型。体外细胞毒性研究表明EAP的IC50 62µg /毫升。结论:结果表明,enthanolic提取ofAP具有镇痛、抗炎和发现细胞毒性体外培养模型。