Abstract

Enhanced oxidation of salbutamol sulphate at acetylene black-dihexadecyl hydrogen phosphate composite film electrode and its analytical applications

Author(s):Xiaofeng Yang, Fang Wang, Shengshui Hu

An electroanalytical method for determination of salbutamol sulphate was established on basis of enhanced oxidation of salbutamol sulphate at an acetylene black-dihexadecyl hydrogen phosphate composite film modified glassy carbon electrode (AB-DHP/GCE).Under optimalworking conditions, this oxidation current was proportional to salbutamol sulphate concentration range from4.010-7 to 7.510-6mol L-1 and from7.510-6 to 1.010-4mol L-1with a low detection limit of 1.010-7 mol L-1 for 2 min accumulation at open circuit (S/N = 3). The proposed method was applied to the determination of salbutamol sulphate in tablets and the results were satisfying.