摘要
年龄相关性白内障患者血浆维生素C浓度的评价
作者(年代):Jaskiran Kaur, Sahiba Kukreja, Kawalinder Girgla, Amandeep Kaur白内障是一种视力损害疾病，其特征是晶状体逐渐增厚。它是当今世界致盲的主要原因之一。紫外线等氧化物质是白内障最重要的诱因之一。膳食中的抗氧化维生素，特别是维生素C(抗坏血酸)，可以在预防老年性白内障的发生或发展中发挥作用。这项研究的目的是发现白内障患者的血液氧化应激——丙二醛(MDA)和抗坏血酸(维生素c)水平之间的相关性。根据年龄标准将患者细分为3组。I组45-55岁，ii组56-65岁，III组66-75岁。50名年龄匹配的健康受试者作为对照。用酸性磷钨酸比色法测定血浆抗坏血酸水平。3个试验组血浆抗坏血酸平均水平分别为0.69±0.08、0.70±0.08、0.65±0.10 mg/dl，对照组分别为0.86±0.07、0.84±0.08、0.86±1.10 mg/dl。 The results were statistically analyzed using studentt test. The decrease in Plasma ascorbic acid level was highly significant in group II and III as compared to control group (p<0.001). This study revealed that plasma vitamin C level in patients with senile cataract was lower than normal individuals. The concentration of vitamin Cwas not related to the type of cataract. Aging was associated with a reduction in plasma ascorbic acid levels. Elderly patients should be advised to take fresh vegetables and fruits rich in vitamin C or other supplements to improve the plasma levels.
